Calciphylaxis in Man

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Calciphylaxis in man.

A patient with renal failure developed widespread calcification in the thighs after the injection of iron-dextran (Imferon). This is considered as an example of calciphylaxis, a process in which calcium is laid down in parts of the body following the administration of a "challenger." Iron-dextran is a known challenger, and should be used with caution in uraemic subjects, who may be sensitized b...

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Calciphylaxis

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Calciphylaxis

Fig. 1. Dry gangrene of the fingers (A and B) and dusky red discoloration of the right great toe (C) are shown. Progression of the gangrene of the fingers (D and E) and development of gangrenous necrosis of the toes (F) are shown. Plain radiographs demonstrating marked vascular calcification of the hands and feet (G–J). Skin biopsy revealing calcification (K) and microthrombosis (L and M) of sm...

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Calciphylaxis

Figure 1. Right leg with painful ulcer demonstrating thrombosed blood vessels, saponified fat, and ischemic skin necrosis. DESCRIPTION A 56-year-old man presented with a wound of the right leg for 6 weeks that progressed from a linear ulceration with surrounding erythema to an excruciatingly painful ulcer with fat saponification and visible thrombosed vessels. His medical history was significan...

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Nanobacteria-caused mitral valve calciphylaxis in a man with diabetic renal failure.

We have found that nanobacteria, recently discovered Gram-negative atypical bacteria, can cause local calciphylaxis on the mitral valve in a setting of high-calcium X phosphorous product in the blood. We present the case of a 33-year-old man with diabetic renal failure on continuous ambulatory peritoneal dialysis who died as a result of multiple brain infarcts due to embolizations from mitral v...

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ژورنال

عنوان ژورنال: BMJ

سال: 1969

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5658.670